RELUGOLIX INTERMEDIATE

Relugolix Intermediate

Relugolix Intermediate

Blog Article

A.R. Life Science Pvt Ltd: Leading Manufacturer of Relugolix Intermediate


A.R. Life Science Pvt Ltd is a trusted name in the pharmaceutical industry, renowned for manufacturing high-quality intermediates and active pharmaceutical ingredients (APIs). One of their flagship products is Relugolix Intermediate, specifically 3-Amino-6-methoxypyridazine (CAS No. 7252-84-8). This intermediate is pivotal in synthesizing Relugolix, a breakthrough drug in treating hormone-sensitive conditions.

Product Overview: 3-Amino-6-methoxy pyridazine (Relugolix Intermediate)



  • Chemical Name: 3-Amino-6-methoxy pyridazine

  • CAS No.: 7252-84-8

  • Molecular Formula: C5H7N3O

  • Molecular Weight: 125.13 g/mol

  • MDL Number: MFCD01646127

  • Purity/Specification: 98%

  • Storage Conditions: Keep in a dark place. Store sealed in a dry container. Maintain temperature at 2–8°C.


Chemical and Physical Properties



  • Appearance: White to pale yellow crystalline powder

  • Melting Point: 220–225°C

  • Boiling Point: Decomposes upon boiling (~310°C)

  • Solubility: Soluble in water and organic solvents like ethanol and methanol

  • Stability: Chemically stable under recommended storage conditions


Mechanism of Action and Therapeutic Action


Relugolix, synthesized using 3-Amino-6-methoxypyridazine, acts as a gonadotropin-releasing hormone (GnRH) receptor antagonist.

Mechanism of Action:


Relugolix binds to GnRH receptors in the pituitary gland, inhibiting the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This reduces testosterone production in males and estrogen in females, making it practical for hormone-sensitive conditions.

Therapeutic Applications:



  • Prostate Cancer: Helps reduce testosterone levels to slow cancer progression.

  • Uterine Fibroids: Reduces estrogen levels, shrinking fibroids and alleviating associated symptoms like heavy menstrual bleeding.

  • Endometriosis: Alleviates pain and inflammation by lowering estrogen levels.

  • Benefits of 3-Amino-6-methoxy pyridazine (CAS No. 7252-84-8)

  • High Purity: Ensures optimal drug efficacy and consistent performance.

  • Stability: Enables efficient synthesis of Relugolix, contributing to its therapeutic success.

  • Cost-Effectiveness: Facilitates streamlined production of hormone therapy drugs.

  • Therapeutic Reliability: Supports the development of non-invasive treatment options for hormone-related disorders.


Why Choose A.R. Life Science Pvt Ltd?


A.R. Life Science Pvt Ltd stands as a leading manufacturer of Relugolix Intermediate. The company is dedicated to producing pharmaceutical-grade intermediates and APIs, focusing on innovation, quality, and sustainability.

  • Expert Manufacturing: Decades of experience in pharmaceutical intermediate production.

  • Global Standards: Compliance with international quality norms ensures superior product reliability.

  • Timely Deliveries: Equipped with state-of-the-art infrastructure for efficient production and supply.

  • Commitment to Excellence: Strong focus on customer satisfaction and operational transparency.


Conclusion


3-Amino-6-methoxypyridazine (CAS No. 7252-84-8) is a critical intermediate for synthesizing Relugolix, a revolutionary drug in hormone therapy. Its exceptional chemical properties and stability make it indispensable in pharmaceutical manufacturing.

With A.R. Life Science Pvt Ltd's unwavering dedication to quality and innovation, they continue to produce world-class pharmaceutical intermediates and APIs, serving clients globally with reliability and excellence.

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